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EAU 2026: PRIMARY2 – Impact of 68Ga-PSMA-11 PET/CT in the Diagnosis of Prostate Cancer in Men with Equivocal or Non-Suspicious Findings on mpMRI: A Multi-Center, Phase III, Randomized Trial

At EAU 2026, Dr. Buteau and colleagues aimed to demonstrate that 68Ga-PSMA-11 PET/CT could reduce patients requiring biopsy and limit biopsy to targeted cores, without significantly decreasing significant prostate cancer diagnosis. Significant prostate cancer was defined as Gleason score 3+4 (≥10% pattern…

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ProsTIC26: Will PSMA PET Replace Painful Prostate Biopsy? No

Will PSMA PET ever replace prostate biopsy? Before an irreversible treatment, clinicians need more information than a binary determination of whether clinically significant prostate cancer is present. A tissue diagnosis provides answers regarding: False positive results of PSMA PET imaging…

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